Commercial air purifiers are used to provide clean air - typically within a manufacturing or scientific research commercial space - by removing contaminants such as dust, airborne micorbes, aerosol particles and chemical vapors. Commercial systems are designed as either a small, stand-alone unit or a larger unit that can be connected to an HVAC or air handling system in medical, industrial, and commercial industries. A clean-room has a controlled level of contamination that is specified by the number of particles per cubic meter at a specified particle size.

A clean-room environment is typically used in manufacturing or scientific research, that has a low level of environmental pollutants such as dust, airborne microbes, aerosol particles and chemical vapors. More accurately, a clean-room has a controlled level of contamination that is specified by the number of particles per cubic meter at a specified particle size.